myelodysplastic syndrome with 6q deletion as the sole chromosome abnormality in an iranian patient: a case report with review of literature.

نویسندگان

shirin ferdowsi 1. dept. of hematology, iranian blood transfusion organization , tehran, iran.

reza shirkoohi 2. dept. of molecular genetics, cancer research center, cancer institute, imam khomeini hospital complex, tehran university of medical sciences , tehran, iran.

gholamreza toogeh 3. dept. of hematology-oncology and bmt research center, imam khomeini hospital complex, tehran university of medical sciences , tehran, iran.

چکیده

the myelodysplastic syndrome (mds) is a highly heterogenous disorder and karyotype analysis is helpful for diagnostic and prognostic estimation. deletion in long arm chromosome 6 (6q del) as a sole abnormality is a rare event in mds. this is the first case report of del (6q) as the only observed diagnostic change in iran. we also reviewed the literature of this cytogenetic lesion.

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Myelodysplastic Syndrome with 6q Deletion as the Sole Chromosome Abnormality in an Iranian Patient: A Case Report with Review of Literature

BACKGROUND The myelodysplastic syndrome (MDS) is a highly heterogenous disorder and karyotype analysis is helpful for diagnostic and prognostic estimation. Deletion in long arm chromosome 6 (6q del) as a sole abnormality is a rare event in MDS. This is the first case report of del (6q) as the only observed diagnostic change in Iran. We also reviewed the literature of this cytogenetic lesion.

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عنوان ژورنال:
iranian journal of public health

جلد ۴۲، شماره ۱۰، صفحات ۱۱۸۷-۱۱۹۱

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